Publications
2025
Elicker K, Setia G, Quraishi M, Jiang XYZ, Kan L, Flynt AS, Wen J, Wahba L, Lai EC. Recurrent expansion and rapid evolution of the Drosophilid RNAi pathway in testis. bioRxiv [Preprint]. 2025 Nov 29:2025.11.28.691189
Ichikawa K, Shoura MJ, Artiles KL, Jeong DE, Owa C, Kobayashi H, Suzuki Y, Kanamori M, Toyoshima Y, Iino Y, Rougvie AE, Wahba L, Fire AZ, Schwarz EM, Morishita S. CGC1, a new reference genome for Caenorhabditis elegans. Genome Res. 2025 Aug 1;35(8):1902-1918. doi: 10.1101/gr.280274.124. PMID: 40664475; PMCID: PMC12315879.
2024
Ortega, J., Wahba L., Seemann J., Chen, S-U., Fire A., Arur, S. (2024). Pachytene piRNAs control discrete meiotic events during spermatogenesis and restrict gene expression in space and time. Science Advances 40, eadp0466.
Dr. Wahba's Postdoctoral & Graduate School Publications
Wahba L., Hansen L. and Fire A. (2021) An essential role for the piRNA pathway in regulating the ribosomal RNA pool in C. elegans. Developmental Cell 56, 2295-2312.
Yoshimura J., Ichikawa K., Shoura M., Artiles K., Gadbank I., Wahba L., Smith C., Edgley M.,Rougvie A., Fire A., Morishita S. and Schwarz E. (2019) Recompleting the Caenorhabditis elegans genome. Genome Research 29, 1009-1022.
Wahba L.*, Constantino L.*, Tan F., Zimmer A. and Koshland D. (2016) S1-DRIP-seq identifies high expression and polyA tracts as major contributors to R-loop formation. Genes & Development 30, 1327-1338.* denotes equal contribution
Wahba L., Gore S. and Koshland D. (2013) The homologous recombination machinery mediates RNA-DNA hybrid formation and associated chromosome instability. eLife 2:e00505.
Wahba L., Amon J., Koshland D. and Vuica M. (2011) RNase H and multiple RNA biogenesis factors cooperate to prevent RNA-DNA hybrid mediated genome instability. Molecular Cell 44, 978-988.